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High priority zoonosis

Avian Influenza (H5N1)

Influenza A virus subtype causing severe disease in poultry with sporadic spillover to humans. A WHO priority pathogen and one of India's top zoonotic disease surveillance targets.

Pathogen
Influenza A virus (H5N1, H5N6, H7N9 etc.)
Reservoir
Wild aquatic birds → poultry
Incubation
2–17 days (typically 2–5)
CFR (Humans, confirmed)
~50% (WHO)

Transmission & Risk Groups

Spread occurs primarily through direct contact with infected birds, contaminated surfaces, droplets in poultry environments, and (rarely) human-to-human. Live bird markets, backyard poultry, and waterfowl-shorebird interfaces are recurring hotspots.

Highest-risk groups

  • Poultry farm workers and cullers
  • Live bird market workers & transporters
  • Veterinarians, lab personnel
  • Backyard poultry farming households

Symptoms (humans)

  • Fever (often >38°C), cough, sore throat
  • Muscle aches, malaise
  • Severe: pneumonia, respiratory failure, ARDS
  • Conjunctivitis (some subtypes)

Prevention & Control

  • Biosecurity in farms: isolation of birds, controlled feed/water sources, disinfection, restricted access.
  • Culling & compensation: rapid stamping-out with appropriate compensation to ensure reporting.
  • Surveillance: active surveillance in wetlands & live bird markets; passive reporting via Bharat Pashudhan + NADRS.
  • PPE for workers: respirators, gloves, eye protection, post-exposure antivirals.
  • Vaccination: seasonal vaccination of poultry where indicated; seasonal influenza vaccine for at-risk workers.
  • One Health coordination: joint outbreak response between MoHFW, DAHD, MoEFCC, and state forest depts.
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